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Simply, it can cause neurological disorders, including: alzheimer's disease, sclerosis, stroke and etc. also,it can also lead you to death. While endocrine system, as we all know influences our heart beats, tissues, and even ability to make a baby. But in opposite, if we fail to maintain the homeostasis or the equality of temperature and the balance, it develops diabetes, thyroid diseases  or toher sexual dysfunction. 
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