it is called red river of life because blood circulates in our body. so, it was kinda represented by a river.. it was called red, because of hemoglobin that makes the blood really red. about the red river of life in my own explanation, means that we need circulating blood in our bodies in order to live.

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Our BLOOD known as Red river of life.
Blood is a red fluid and it contains the essential substances needed by the body for survival